FIGURE

Fig. 7

ID

ZDB-FIG-120601-53

Publication

Chu et al., 2012 - Overexpression of akt1 enhances adipogenesis and leads to lipoma formation in zebrafish

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Fig. 7

Deregulation of myogenesis-, skeletogenesis-, adipogenesis-, adipocytokine- and inflammation-related genes in Tg(krt4:Hsa.myrAkt1)^cy18.

Comparison of relative expression level of myogenesis/skeletogenesis- (A), adipogenesis- (B), adipocytokine and inflammatory-related (C) gene transcripts between WT and Tg assayed by real-time RT-PCR. Stars labeled above the error bars indicate significant differences as tested by Student’s t-test.*p<0.05, **p<0.01, and ***p<0.001.Visualization of the inflammatory response (red dotted line) in the tail region of both Tg(mpx:GFP)ⁱ¹¹³ (D) and double transgenic progeny derived from Tg(mpx:GFP)ⁱ¹¹³ and Tg(krt4:Hsa.myrAkt1)^cy18 crossing (E).WT, wild type; Tg, Tg(krt4:Hsa.myrAkt1)^cy18.

Expression Data

Genes:	adipoqa adipoqb adipor1a adipor1b adipor2 cebpa col2a1a fabp4a fabp4b il1b lepr lpin1a lpla mgp mmp2 mmp9 myf5 myf6 mylpfa myod1 myog pparg runx2a runx2b scd srebf1 srebf2 tnfa (all 28)
Fish:	AB cy18Tg
Anatomical Terms:	caudal fin whole organism
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cy18Tg; i113Tg
Observed In:	post-vent region
Stage:	Adult

Phenotype Detail

Acknowledgments

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