FIGURE

Fig. 1

ID

ZDB-FIG-240812-1

Publication

Gioacchino et al., 2024 - GATA2 heterozygosity causes an epigenetic feedback mechanism resulting in myeloid and erythroid dysplasia

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Fig. 1

Gata2b+/− kidney marrow (KM) shows erythroid and myeloid dysplasia. (A) Representative pictures of KM smears after May–Grünwald–Giemsa staining of wild-type (WT) KM smears (panels 1 and 2) and gata2b+/− KM smears (panels 3–8). (3) Blebbing in the cytoplasm of proerythroblast; (4) irregular cytoplasm in erythroid precursor; (5) lobed nucleus and micronucleus in erythroblast; (6) blebbing in the cytoplasm of the blast of sorted cell after cytospin; (7) binucleated promyelocyte; and (8) multinucleated promyelocyte. (B) Frequency of dysplastic cells of the erythroid, myeloid and lymphoid lineage in KM smears of WT (n = 8) and gata2b+/− (n = 8) zebrafish. ***p < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Br. J. Haematol.