FIGURE

Fig. 2

ID
ZDB-FIG-100225-19
Publication
Rai et al., 2010 - Dnmt3 and G9a cooperate for tissue-specific development in zebrafish
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Fig. 2

Distinct tissue-specific developmental defects in dnmt1 and dnmt3 morphants. A, C, and E, whole mount in situ analysis of dhand (at 48 hpf) (A), fabp2, trypsin, fabp10, insulin, and trypsin (C), and irbp (E) (all at 96 hpf) in dnmt1, dnmt3, and control morphants. In panel A, arrows show loss of last two pharyngeal pouches in dnmt3 morphants. In panel C, arrows point to expression of gata6 in the pancreas. B, Alcian Blue staining of Control, dnmt1, or dnmt3 morphants at 96 hpf shows loss of jaw structure in dnmt1 morphants but not in dnmt3 morphants. D, toluidine blue staining of histological cross-sections within the dnmt3 morphant retinas at 80 hpf. Note the loss of organization of different retinal layers in dnmt3 morphants. F, quantitative RT-PCR for Opsin Shortwave 1 and Opsin Shortwave 2 in control, dnmt1, or dnmt3 morpholino-injected embryos at 96 hpf.

Expression Data
Genes: (all 9)
Fish:
Knockdown Reagents:
Anatomical Terms: (all 9)
Stage Range: Long-pec to Day 4

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In: (all 9)
Stage Range: Long-pec to Day 4

Phenotype Detail
Acknowledgments
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Open Access.
Full text @ J. Biol. Chem.
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