Gene

opn1sw2

ID
ZDB-GENE-990604-40
Name
opsin 1 (cone pigments), short-wave-sensitive 2
Symbol
opn1sw2 Nomenclature History
Previous Names
  • SWS2 (1)
  • bluops
  • zfblue
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled photoreceptor activity. Acts upstream of or within detection of visible light and phototaxis. Located in photoreceptor outer segment. Is expressed in several structures, including endocrine system; heart; integument; photoreceptor cell; and visual system.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
81 figures from 52 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Wang et al., 2023
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa38844Allele with one point mutationUnknownPremature StopENU
sa41842Allele with one point mutationUnknownPremature StopENU
zf3924Allele with one delinsExon 1UnknownCRISPR
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Sequence Targeting Reagents
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Human Disease
Associated With opn1sw2 Human Ortholog
No data available
Associated With opn1sw2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR027430 Visual pigments (opsins) retinal binding site
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR001521 Opsin, blue sensitive
Family IPR001760 Opsin
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Domain Details Per Protein
Protein Additional Resources Length GPCR, rhodopsin-like, 7TM G-protein coupled receptor opsins G protein-coupled receptor, rhodopsin-like Opsin Opsin, blue sensitive Visual pigments (opsins) retinal binding site
UniProtKB:Q9W6A8 InterPro 354
UniProtKB:A8E5J4 InterPro 354
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA opn1sw2-201 (1) Ensembl 1,413 nt
mRNA opn1sw2-202 (1) Ensembl 888 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-opn1sw2 polyclonal Rabbit
  • IHC
  • WB
48
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Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(-1.1opn1sw2:EGFP)
  • opn1sw2
  • Danio rerio
1 (2)
Tg(-1.7opn1sw2:EGFP)
  • opn1sw2
  • Danio rerio
1 (2)
Tg2(opn1sw2:mCherry)
  • opn1sw2
  • Danio rerio
1 (6)
Tg(-3.5opn1sw2:EGFP)
  • opn1sw2
  • Danio rerio
1 (18)
Tg(-3.5opn1sw2:tetxlc-CFP)
  • opn1sw2
  • Danio rerio
1 (2)
Tg(-5.2opn1sw2:EGFP)
  • opn1sw2
  • Danio rerio
1 (3)
Tg(opn1sw2:GFP)
  • opn1sw2
  • Danio rerio
1Noel et al., 2017
Tg(opn1sw2:KALTA4)
  • opn1sw2
  • Danio rerio
2 (3)
Tg(opn1sw2:mCherry)
  • opn1sw2
  • Danio rerio
1 (19)
Tg(opn1sw2:NfsB-mCherry)
  • opn1sw2
  • Danio rerio
1Zebrafish Nomenclature Committee
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-13A21
Contained inBACDKEY-245F22ZFIN Curated Data
EncodescDNAMGC:73033ZFIN Curated Data
EncodescDNAMGC:77574ZFIN Curated Data
EncodescDNAMGC:174476ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
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