FIGURE

Figure 7

ID

ZDB-FIG-250328-25

Publication

Jia et al., 2025 - FRET-Based Sensor Zebrafish Reveal Muscle Cells Do Not Undergo Apoptosis in Starvation or Natural Aging-Induced Muscle Atrophy

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Figure 7

Apoptosis was not involved in the process of muscle atrophy during natural aging. A) The muscle atrophy model induced by natural aging. B) The ages of zebrafish when they were sacrificed. C) Morphologies of healthy young zebrafish and naturally aged zebrafish with muscle atrophy. D) The quantified results show the decrease in the body size of atrophied zebrafish (n = 9 zebrafish for each group). E) The decrease of the diameter of muscle cells in atrophied zebrafish. F) The quantified results show the decrease of the muscle cells in atrophied zebrafish (n = 90 cells from 9 zebrafish for each group). G) The mRNA levels of muscle atrophy markers in young and atrophied zebrafish. H) FRET imaging shows no obvious blue apoptotic signals from atrophied zebrafish. I) TUNEL assays show no muscle cell apoptosis in atrophied zebrafish. The size of each scale bar is indicated in each image. ^**p < 0.01, ^****p < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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