Fig. 1 - Supplemental 2
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- Kondrychyn et al., 2025 - Combined forces of hydrostatic pressure and actin polymerization drive endothelial tip cell migration and sprouting angiogenesis
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scRNA-seq analysis of kdrl-positive cells from 24 hpf, 34 hpf, and 3 dpf zebrafish. (A, B) UMAP plots of 5576 cells from 24 hpf Tg(kdrl:mCherry) (Gurung et al., 2022), 1475 cells from 34 hpf Tg(kdrl:EGFP)s843 zebrafish, and 1692 cells from 3 dpf Tg(kdrl:EGFP)s843 zebrafish (A) showing 16 distinct clusters (B). Classifications were based on previously known marker genes that are enriched in each cluster. (C–F) UMAP feature plots showing expression of kdrl (C), etsrp/etv2 (D), aqp1a.1 (E), and aqp8a.1 (F). (G, H) Violin plots showing expression of aqp1a.1 (G) and aqp8a.1 (H) in different cell populations. |