Transgenic Construct

Tg(myl7:Kaede)

ID

ZDB-TGCONSTRCT-090602-1

Name

Tg(myl7:Kaede)

Previous Names

Tg(myl7:kaede)

Type

engineered_plasmid

Regulatory Regions

myl7 (1)

Coding Sequences

Kaede (1)

Contains Sequences

None

Note

None

Plasmid Map

None

Genomic Features

That Utilize Tg(myl7:Kaede) Construct

Genomic Feature	Affected Genomic Regions
sd22Tg

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Transgenics

That Utilize Tg(myl7:Kaede) Construct

Fish	Affected Genomic Regions	Phenotype	Gene Expression
nkx2.5^vu179/vu179; sd22Tg	nkx2.5		Fig. 9 from Targoff et al., 2013
nkx2.5^vu179/vu179; sd22Tg + MO1-nkx2.7			Fig. 9 from Targoff et al., 2013
nr2f1a^el512/el512; sd22Tg	nr2f1a	Fig. 2 from Duong et al., 2017
pd3Tg; sd22Tg		Fig. 4 from Rydeen et al., 2016	Fig. 4 from Rydeen et al., 2016
pd3Tg; sd22Tg + MO1-cyp26c1 + MO2-cyp26c1 + MO4-cyp26a1 + MO5-cyp26a1		Fig. 4 from Rydeen et al., 2016	Fig. 4 from Rydeen et al., 2016

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Sequence Information

Other Construct Pages

None

Citations

Include unpublished citations

Holowiecki, A., Linstrum, K., Ravisankar, P., Chetal, K., Salomonis, N., Waxman, J.S. (2020) Pbx4 limits heart size and fosters arch artery formation through partitioning second heart field progenitors and restricting proliferation. Development (Cambridge, England). 147(5):
Song, Y.C., Dohn, T.E., Rydeen, A.B., Nechiporuk, A.V., Waxman, J.S. (2019) HDAC1-mediated repression of the retinoic acid-responsive gene ripply3 promotes second heart field development. PLoS Genetics. 15:e1008165
Duong, T.B., Ravisankar, P., Song, Y.C., Gafranek, J.T., Rydeen, A.B., Dohn, T.E., Barske, L.A., Crump, J.G., Waxman, J.S. (2017) Nr2f1a balances atrial chamber and atrioventricular canal size via BMP signaling-independent and -dependent mechanisms. Developmental Biology. 434(1):7-14
Rydeen, A.B., Waxman, J.S. (2016) Cyp26 Enzymes Facilitate Second Heart Field Progenitor Addition and Maintenance of Ventricular Integrity. PLoS Biology. 14:e2000504
Cavanaugh, A.M., Huang, J., Chen, J.N. (2015) Two developmentally distinct populations of neural crest cells contribute to the zebrafish heart. Developmental Biology. 404(2):103-12
Zeng, X.X., Yelon, D. (2014) Cadm4 Restricts the Production of Cardiac Outflow Tract Progenitor Cells. Cell Reports. 7(4):951-60
Targoff, K.L., Colombo, S., George, V., Schell, T., Kim, S.H., Solnica-Krezel, L., and Yelon, D. (2013) Nkx genes are essential for maintenance of ventricular identity. Development (Cambridge, England). 140(20):4203-4213
de Pater, E., Clijsters, L., Marques, S.R., Lin, Y.F., Garavito-Aguilar, Z.V., Yelon, D., and Bakkers, J. (2009) Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart. Development (Cambridge, England). 136(10):1633-1641

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