ZFIN Morpholino: MO1-myod1

Target Location

Genome Build: GRCz11Chromosome: 25

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-myod1

No data available

Phenotype

Phenotype resulting from MO1-myod1

Phenotype	Fish	Figures
cephalic musculature aplastic, abnormal	WT + MO1-myod1	Fig. 3 from Hinits et al., 2009
cephalic musculature decreased amount, abnormal	WT + MO1-myod1	Fig. 4 , Fig. 7 , Fig. 8 from Lin et al., 2006
esophagus skeletal muscle cell poorly differentiated, abnormal	WT + MO1-myod1	Fig. 4 from Minchin et al., 2013
fast muscle cell decreased amount, abnormal	WT + MO1-myod1	Fig. 6 from Osborn et al., 2011
head decreased size, abnormal	twu3Tg + MO1-myod1	Fig. 1 from Lin et al., 2013

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Phenotype of all Fish created by or utilizing MO1-myod1

Phenotype	Fish	Conditions	Figures
fast muscle cell decreased amount, abnormal	WT + MO1-myod1	standard conditions	Fig. 6 from Osborn et al., 2011
cephalic musculature aplastic, abnormal	WT + MO1-myod1	standard conditions	Fig. 3 from Hinits et al., 2009
head muscle poorly differentiated, abnormal	WT + MO1-myod1	standard conditions	Fig. 4 from Minchin et al., 2013
head muscle hypoplastic, abnormal	WT + MO1-myod1	standard conditions	Fig. 6 from Osborn et al., 2011
cephalic musculature decreased amount, abnormal	WT + MO1-myod1	standard conditions	Fig. 4 , Fig. 7 , Fig. 8 from Lin et al., 2006

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Citations

Include unpublished citations

Paulissen, E., Martin, B.L. (2022) Myogenic regulatory factors myod and Myf5 are required for dorsal aorta formation and angiogenic sprouting. Developmental Biology. 490:134-143
Row, R.H., Pegg, A., Kinney, B., Farr, G.H., Maves, L., Lowell, S., Wilson, V., Martin, B.L. (2018) BMP and FGF signaling interact to pattern mesoderm by controlling basic helix-loop-helix transcription factor activity. eLIFE. 7
Chen, J.W., Galloway, J.L. (2014) The development of zebrafish tendon and ligament progenitors. Development (Cambridge, England). 141:2035-45
Devakanmalai, G.S., Zumrut, H.E., and Ozbudak, E.M. (2013) Cited3 activates Mef2c to control muscle cell differentiation and survival. Biology Open. 2(5):505-514
Lin, C.Y., Lee, H.C., Chen, H.C., Hsieh, C.C., and Tsai, H.J. (2013) Normal Function of Myf5 During Gastrulation Is Required for Pharyngeal Arch Cartilage Development in Zebrafish Embryos. Zebrafish. 10(4):486-99
Minchin, J.E., Williams, V.C., Hinits, Y., Low, S., Tandon, P., Fan, C.M., Rawls, J.F., and Hughes, S.M. (2013) Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. Development (Cambridge, England). 140(14):2972-2984
Nord, H., Skalman, L.N., and von Hofsten, J. (2013) Six1 regulates proliferation of Pax7-positive muscle progenitors in zebrafish. Journal of Cell Science. 126(Pt 8):1868-80
Shwartz, Y., Farkas, Z., Stern, T., Aszódi, A., and Zelzer, E. (2012) Muscle contraction controls skeletal morphogenesis through regulation of chondrocyte convergent extension. Developmental Biology. 370(1):154-163
Burguière, A.C., Nord, H., and von Hofsten, J. (2011) Alkali-like myosin light chain-1 (myl1) is an early marker for differentiating fast muscle cells in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 240(7):1856-1863
Hinits, Y., Williams, V.C., Sweetman, D., Donn, T.M., Ma, T.P., Moens, C.B., and Hughes, S.M. (2011) Defective cranial skeletal development, larval lethality and haploinsufficiency in Myod mutant zebrafish. Developmental Biology. 358(1):102-12

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