Gene

ela3l

ID
ZDB-GENE-060710-2
Name
elastase 3 like
Symbol
ela3l Nomenclature History
Previous Names
  • ela2al
  • elaA (1)
  • elastaseA (1)
  • trypsin 5 (1)
  • wu:fd58f03
  • zgc:109943
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Is expressed in digestive system; exocrine pancreas; and pancreas. Orthologous to human CELA3A (chymotrypsin like elastase 3A) and CELA3B (chymotrypsin like elastase 3B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la024923TgTransgenic insertionUnknownUnknownDNA
sa18102Allele with one point mutationUnknownPremature StopENU
sa20417Allele with one point mutationUnknownPremature StopENU
sa26473Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With ela3l Human Ortholog
No data available
Associated With ela3l Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR018114 Serine proteases, trypsin family, histidine active site
Active_site IPR033116 Serine proteases, trypsin family, serine active site
Domain IPR001254 Serine proteases, trypsin domain
Family IPR001314 Peptidase S1A, chymotrypsin family
Family IPR050850 Peptidase S1 family, Elastase subfamily
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Domain Details Per Protein
Protein Additional Resources Length Peptidase S1A, chymotrypsin family Peptidase S1 family, Elastase subfamily Peptidase S1, PA clan Peptidase S1, PA clan, chymotrypsin-like fold Serine proteases, trypsin domain Serine proteases, trypsin family, histidine active site Serine proteases, trypsin family, serine active site
UniProtKB:Q504D4 InterPro 201
UniProtKB:A0A8M9QDY3 InterPro 270
UniProtKB:A2BGP5 InterPro 269
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ela3l-201 (1) Ensembl 973 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg1(ela3l:Cre,cryaa:Venus)
  • Danio rerio
1Zebrafish Nomenclature Committee
Tg(ela3l:casp8,ela3l:Crimson)
  • ela3l
  • Danio rerio
1 (3)
Tg(ela3l:Cre,cryaa:Venus)
  • Danio rerio
1 (4)
Tg(ela3l:Crimson)
  • ela3l
  • Danio rerio
1 (2)
Tg(ela3l:EGFP)
  • ela3l
  • Danio rerio
2 (137)
Tg(ela3l:H2B-EGFP)
  • ela3l
  • Danio rerio
1 (2)
Tg(ela3l:Hsa.HBEGF_I117V_L148V,ela3l:Crimson)
  • ela3l
  • Danio rerio
  • Homo sapiens
1Schmitner et al., 2017
Tg(ela3l:mCherry,myl7:EGFP)
  • Danio rerio
1Freudenblum et al., 2018
Tg(ela3l:TagRFP-NTR)
  • ela3l
  • Danio rerio
1 (2)
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-214J8ZFIN Curated Data
EncodesESTfd58f03
EncodescDNAMGC:109943ZFIN Curated Data
EncodescDNAMGC:192180ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
No data available
Citations
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