Gene

msgn1

ID
ZDB-GENE-030722-1
Name
mesogenin 1
Symbol
msgn1 Nomenclature History
Previous Names
  • mespo (1)
  • pMeso1a (1)
  • wu:fc39h09
  • zgc:109769
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within paraxial mesodermal cell differentiation; regulation of transcription by RNA polymerase II; and somatic muscle development. Predicted to be active in nucleus. Is expressed in several structures, including margin; mesoderm; myoblast; tail bud; and telencephalon. Orthologous to human MSGN1 (mesogenin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
25 figures from 17 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
fh273Allele with one point mutationUnknownPremature StopENU
msgn1_unrecoveredAllele with one point mutationUnknownUnknownENU
sa33349Allele with one point mutationUnknownPremature StopENU
1 - 3 of 3
Show
Sequence Targeting Reagents
1 - 3 of 3
Show
Human Disease
Associated With msgn1 Human Ortholog
No data available
Associated With msgn1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR040259 Mesogenin/MesP
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
1 - 3 of 3
Domain Details Per Protein
Protein Additional Resources Length Helix-loop-helix DNA-binding domain superfamily Mesogenin/MesP Myc-type, basic helix-loop-helix (bHLH) domain
UniProtKB:Q90ZL1 InterPro 131
1 - 1 of 1
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 4
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA msgn1-201 (1) Ensembl 1,971 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(hsp70l:HA-msgn1,Xla.Cryg:ECFP)
  • Danio rerio
  • Xenopus laevis
1 (2)
Tg(hsp70l:msgn1-2A-NLS-KikGR)
  • Danio rerio
1 (2)
Tg(msgn1:Cre-ERT2)
  • msgn1
  • Danio rerio
1 (5)
Tg(msgn1:GAL4-VP16)
  • msgn1
  • Danio rerio
1Yabe et al., 2023
Tg(msgn1:NLS-Kaede)
  • msgn1
  • Danio rerio
1 (3)
1 - 5 of 5
Show
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-222H17ZFIN Curated Data
Contained inBACCH211-249I14ZFIN Curated Data
EncodesESTfc39h09
EncodesESTwz13339
EncodescDNAMGC:109769ZFIN Curated Data
EncodescDNAMGC:174017ZFIN Curated Data
EncodescDNAMGC:192585ZFIN Curated Data
1 - 7 of 7
Show
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanMSGN12
Amino acid sequence comparison (1)
MouseMsgn112
Amino acid sequence comparison (1)
Citations
1 - 10 of 39
Show