Engineered Region
ERT2
- ID
- ZDB-EREGION-110816-12
- Name
- ERT2
- Symbol
- ERT2
- Previous Names
- None
- Location
- Unmapped
- Note
-
A mutant estrogen ligand-binding domain (ERT2) that requires the presence of tamoxifen for activity.
Constructs
Citations
- Bouwman, M., de Bakker, D.E.M., Honkoop, H., Giovou, A.E., Versteeg, D., Boender, A.R., Nguyen, P.D., Slotboom, M., Colquhoun, D., Vigil-Garcia, M., Kooijman, L., Janssen, R., Hooijkaas, I.B., Günthel, M., Visser, K.J., Klerk, M., Zentilin, L., Giacca, M., Kaslin, J., Boink, G.J.J., van Rooij, E., Christoffels, V.M., Bakkers, J. (2025) Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration. Nature cardiovascular research. 4(1):64-82
- Gang, K., Chen, Q., Sun, J., Zhang, T., Cai, P., Ni, R., Ma, J. (2025) Khdrbs1 drives redifferentiation of bipotential progenitor cell by inhibiting p53 in zebrafish biliary-mediated liver regeneration. Development (Cambridge, England). :
- Rao, A., Russell, A., Segura-Bermudez, J., Franz, C., Dockery, R., Blatnik, A., Panten, J., Zevallos, M., McNulty, C., Pietrzak, M., Goldman, J.A. (2025) A cardiac transcriptional enhancer is repurposed during regeneration to activate an anti-proliferative program. Development (Cambridge, England). :
- Scerbo, P., Tisserand, B., Delagrange, M., Debare, H., Bensimon, D., Ducos, B. (2025) In vivo targeted and deterministic single-cell malignant transformation. eLIFE. 13:
- She, P., Gao, B., Li, D., Wu, C., Zhu, X., He, Y., Mo, F., Qi, Y., Jin, D., Chen, Y., Zhao, X., Lin, J., Hu, H., Li, J., Zhang, B., Xie, P., Lin, C., Christoffels, V.M., Wu, Y., Zhu, P., Zhong, T.P. (2025) The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to maintain cardiac homeostasis. Nature communications. 16:232232
- Apolínová, K., Pérez, F.A., Dyballa, S., Coppe, B., Mercader Huber, N., Terriente, J., Di Donato, V. (2024) ZebraReg-a novel platform for discovering regulators of cardiac regeneration using zebrafish. Frontiers in cell and developmental biology. 12:13844231384423
- Bailon-Zambrano, R., Keating, M.K., Sales, E.C., Nichols, A.R., Gustafson, G.E., Hopkins, C.A., Kocha, K.M., Huang, P., Barske, L., Nichols, J.T. (2024) The sclerotome is the source of the dorsal and anal fin skeleton and its expansion is required for median fin development. Development (Cambridge, England). 151(24):
- Chávez, M.N., Arora, P., Meer, M., Marques, I.J., Ernst, A., Morales Castro, R.A., Mercader, N. (2024) Spns1-dependent endocardial lysosomal function drives valve morphogenesis through Notch1-signaling. iScience. 27:111406111406
- Dai, C., Zhang, Y., Gong, Y., Bradley, A., Tang, Z., Sellick, K., Shrestha, S., Spears, E., Covington, B.A., Stanley, J., Jenkins, R., Richardson, T.M., Brantley, R.A., Coate, K., Saunders, D.C., Wright, J.J., Brissova, M., Dean, E.D., Powers, A.C., Chen, W. (2024) Hyperaminoacidemia from interrupted glucagon signaling increases pancreatic acinar cell proliferation and size via mTORC1 and YAP pathways. iScience. 27:111447111447
- Dong, Y., Yang, Y., Wang, H., Feng, D., Nist, E., Yapundich, N., Spurlock, B., Craft, M., Qian, L., Liu, J. (2024) Single-cell chromatin profiling reveals genetic programs activating proregenerative states in nonmyocyte cells. Science advances. 10:eadk4694
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