Gene

arr3b

ID
ZDB-GENE-030616-74
Name
arrestin 3b, retinal (X-arrestin)
Symbol
arr3b Nomenclature History
Previous Names
  • arr3 (1)
  • si:bz46j2.6
  • zgc:73331
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor binding activity. Predicted to be involved in G protein-coupled receptor internalization and visual perception. Predicted to act upstream of or within signal transduction. Is expressed in neural plate; optic primordium; optic vesicle; photoreceptor cell; and visual system. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (arrestin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 10 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
No data available
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-arr3bN/A (3)
MO2-arr3bN/ARenninger et al., 2011
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Human Disease
Associated With arr3b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myopia 26, X-linked, female-limited 301010
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Associated With arr3b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017864 Arrestin, conserved site
Domain IPR011021 Arrestin-like, N-terminal
Domain IPR011022 Arrestin C-terminal-like domain
Family IPR000698 Arrestin
Homologous_superfamily IPR014752 Arrestin-like, C-terminal
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Domain Details Per Protein
Protein Additional Resources Length Arrestin Arrestin, conserved site Arrestin C-terminal-like domain Arrestin-like, C-terminal Arrestin-like, N-terminal Arrestin, N-terminal Immunoglobulin E-set
UniProtKB:Q6PBM9 InterPro 362
UniProtKB:A0AB32T483 InterPro 364
UniProtKB:A0AB32T7V0 InterPro 366
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 14
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA arr3b-201 (1) Ensembl 1,755 nt
mRNA arr3b-202 (1) Ensembl 3,584 nt
mRNA arr3b-203 (1) Ensembl 728 nt
ncRNA arr3b-003 (1) Ensembl 1,029 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-arr3b Chicken
  • IHC
5
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-285J6ZFIN Curated Data
Contained inBACRP71-46J2ZFIN Curated Data
EncodescDNAMGC:73331ZFIN Curated Data
EncodescDNAMGC:173982ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanARR3X
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MouseArr3X
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 10 of 22
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