FIGURE

FIGURE 6

ID

ZDB-FIG-250501-59

Publication

Konar et al., 2025 - Analysis of the senescence secretome during zebrafish retina regeneration

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 6

Regeneration specific secretome signature. InteractiVenn based analysis was used to determine the presence of a conserved secretome signature. (A) Analysis of upregulated SASP factors and senescence markers from 4 acute damage datasets identified 31 conserved genes, referred to as the SASP-related Regeneration Factors (SRRFs). (B) Analysis of upregulated SASP factors and senescence markers in chronic damage datasets identified 3 conserved genes. (C) STRING analysis of the SRRFs showed both predicted and conserved protein-protein relationships between 25 of the 31 genes in the SRRF. (D) Reactome analysis of the SRRFs showed enrichment in processes related to antigen presentation, cellular transport, immune system processing, and aggrephagy.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Aging