FIGURE

Fig. 2

ID

ZDB-FIG-250408-11

Publication

Lv et al., 2025 - Angiogenic factor AGGF1 is a general splicing factor regulating angiogenesis and vascular development by alternative splicing of SRSF6

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Fig. 2

AGGF1 knockdown promotes extensive remodeling of gene expression in endothelial cells and identification of differential expressed genes (DEGs) between HPAEC transfected with AGGF1-specific siRNA (siAGGF1) and negative control siRNA (siNC) by full-length cDNA sequencing. (A) Principal compartment analysis of sequencing data from HPAEC transfected with siAGGF1 and siNC. (B) Volcano plot of DEGs in siAGGF1 HPAEC compared with siNC HPAEC. (C) Heatmap showing the correlation between the identified DEGs. Each column represents a sample, and each row represents a gene. (D) GO functional enrichment analysis of DEGs. (E) KEGG enrichment analysis of DEGs. Down, downregulated DEGs; Up, upregulated DEGs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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