FIGURE

Fig. 4

ID

ZDB-FIG-231127-97

Publication

Zhong et al., 2023 - Eurycomanone stimulates bone mineralization in zebrafish larvae and promotes osteogenic differentiation of mesenchymal stem cells by upregulating AKT/GSK-3β/β-catenin signaling

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Network pharmacological analysis for EN related to osteoporosis. Venn diagram of (a) EN targets and (b) OP-related genes. (c) Volcano plot of DEGs obtained from GSE35958. (d) Venn diagram of target genes of EN in OP. (e) PPI network of EN targets in OP. (f) Venn diagram of hub genes of EN in OP. (g) Target–signaling pathway/biological process interaction network of EN in OP. Note: left single node, EN; right single node, OP; middle nodes in grid arrangement, overlapping EN-OP targets; upward side nodes in circular arrangement, biological process; downward side nodes in circular arrangement, signaling pathways. (h) Biological process (BP). (i) Molecular function (MF). (j) Cellular component (CC). (k) KEGG pathway. DEGs, differentially expressed genes; EN, eurycomanone; OP, osteoporosis; PPI, protein–protein interaction; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Orthop Translat