FIGURE

Fig. 2

ID

ZDB-FIG-221018-224

Publication

Cai et al., 2021 - Dhx15 regulates zebrafish definitive hematopoiesis through the unfolded protein response pathway

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Fig. 2

Dhx15^−/− zebrafish displayed defective definitive hematopoiesis in CHT. A‐B’, WISH analysis of cmyb expression in dhx15^+/+ and dhx15^−/− at 3 dpf (A, A’) and 4 dpf (B, B’). C‐F’, WISH analysis of mpx (C, C’), l‐plastin (D, D’), hbae1 (E, E’), rag1 (F, F’) expression in dhx15^+/+ and dhx15^−/− zebrafish. G‐I’, WISH analysis of cmyb expression in dhx15^+/+ and dhx15^−/− zebrafish at 36 hpf (G, G’), 48 hpf (H, H’), 60 hpf (I, I’). Black arrows indicate CHT; red arrows indicate ventral wall of dorsal aorta; red arrowheads indicate thymus. CHT, caudal hematopoietic tissue; dpf: days post fertilization; hpf, hours post fertilization; WISH, whole‐mount in situ hybridization

Expression Data

Genes:	hbbe1.1 lcp1 mpx myb rag1
Fish:	AB dhx15^{zf3775/zf3775} (AB)
Anatomical Terms:	caudal hematopoietic tissue caudal hematopoietic tissue myeloid cell caudal hematopoietic tissue neutrophil nucleate erythrocyte thymus ventral wall of dorsal aorta (all 6)
Stage Range:	Prim-25 to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	dhx15^{zf3775/zf3775} (AB)
Observed In:	caudal hematopoietic tissue caudal hematopoietic tissue myeloid cell caudal hematopoietic tissue neutrophil definitive hemopoiesis thymus
Stage Range:	Pec-fin to Day 4

Phenotype Detail

Acknowledgments

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