FIGURE

Fig. 7

ID
ZDB-FIG-210703-17
Publication
Mauri et al., 2021 - The adaptor protein Grb2b is an essential modulator for lympho-venous sprout formation in the zebrafish trunk
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Fig. 7

In the absence of arteries, cells fail to sprout in grb2b mutants. a–c Confocal projections of plcγ-1 MO injected embryos. All vessels are shown in green (fli:GFP). d Sprout quantification at 48hpf of embryos from a tabula rasa in-cross, injected with a plcγ-1 MO. plcγ-1 MO injection inhibits primary sprouting, allowing quantification/visualization of secondary sprouts in absence of arteries. The number of lympho-venous sprouts is significantly decreased in tabula rasa mutants. wt: n = 4; het: n = 32; mut: n = 24. ****Between wt and mut: P value  < 0.0001 (Mann–Whitney); ****Between het and mut: P value < 0.0001 (Mann–Whitney); ns not significant. MO morpholino. Scale bars: 50 µm. Data in d are mean ± sd
Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage: Long-pec

Phenotype Detail
Acknowledgments
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