FIGURE

Fig. 4

ID

ZDB-FIG-131009-24

Publication

Drummond et al., 2013 - The role of Zic transcription factors in regulating hindbrain retinoic acid signaling

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Fig. 4

Retinoic acid-responsive gene expression in Zic morpholino-injected embryos. mRNA transcript expression of RA-dependent markers meis3 and otx2(A, B), hnf1ba(C, D), hoxd4a(E, F), and hoxb1a(G, H) were compared in control uninjected (A, C, E, G) and Zic2a;Zic2b;Zic3MO-injected embryos (B, D, F, H). Although hoxb1a and hnf1ba are largely unchanged, a decrease in meis3 and hoxd4a is observed in Zic morpholino-injected embryos. All images are of 10.5 hpf embryos in dorsal views with anterior oriented to top.

Expression Data

Genes:	hnf1ba hoxb1a hoxd4a meis3 otx2b
Fish:	WT WT + MO2-zic2b + MO2-zic3 + MO3-zic2a
Knockdown Reagents:	MO2-zic2b MO2-zic3 MO3-zic2a
Anatomical Terms:	anatomical structure hindbrain neural plate
Stage:	1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.