FIGURE

Fig. 4

ID

ZDB-FIG-130109-9

Publication

Ichimura et al., 2012 - Structural disorganization of pronephric glomerulus in zebrafish mpp5a/nagie oko mutant

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Fig. 4

mpp5a^m520 mutants and tnnt2a-ATG morphants display a similar structural disorganization of pronephric glomerulus. A: In 4-dpf wild-type embryos, the pronephric glomerulus contains several glomerular capillaries together with mesangium, which is arborized in shape. Podocytes and GBM cover the glomerular capillaries and mesangium en bloc. In both 4-dpf mpp5a^m520 mutants (B) and tnnt2a-ATG morphants (C), the extremely dilated dorsal aorta (DA) lies between a pair of glomerular primordia, which do not contain any fine glomerular capillaries or mesangium. NC, notochord. Scale bar = 500 nm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	pals1a^m520/m520 WT + MO1-tnnt2a
Knockdown Reagent:	MO1-tnnt2a
Observed In:	dorsal aorta pronephric glomerular capillary pronephric glomerulus pronephros development
Stage:	Day 4

Phenotype Detail

Acknowledgments

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