ZFIN Image: McLaurin et al., 2025, FIGURE 3

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Figure Caption

FIGURE 3

Coilin reduction alters the expression of miRNAs that contribute to the innate immune response. Small RNA seq analysis was conducted and miRNAs significantly dysregulated (p ≤ 0.1) in both coilin 2 and coilin A siRNA conditions compared to control (N) siRNA, treated with DMSO are shown. (A, C) Venn diagram showing the number of differentially expressed miRNA genes across coilin 2 (I2) and coilin A (IA) KDs under DMSO or LPS treatment compared to control (N) KD. (B, D) Tables of subsets of miRNAs found to be dysregulated under both coilin I2 and coilin IA KDs with DMSO or LPS treatment compared to control (N) KD. Immunity‐related miRNAs that are upregulated (green) or downregulated (red) in both coilin KD conditions compared to control siRNA are indicated by plus sign (+).

Acknowledgments

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