ZFIN Image: Prill et al., 2025, Figure 1

Image

Figure Caption

Figure 1

Still heart mutant hearts do not loop and display an expansion of cardiac jelly. At 48 hpf, wild-type hearts have looped, with the ventricle and atrium chambers in different planes of focus (A). Unlike wild-type, our still heart mutant hearts do not loop, which allows for easy visualization of both chambers in a single plane of focus at 48 hpf (B). Wild-type hearts (C) display a thin layer of cardiac jelly (CJ) between the endocardial (END) and myocardial (MYO) layers when compared to still heart mutant hearts (D). Panels C and D are magnifications of the atrial walls from panels A and B, respectively. Quantitative PCR analysis of hyaluronan synthase 2 (has2) at 48 hpf showed that the relative fold change in expression of has2 was significantly higher in still heart mutants when compared to wild-type embryos (E). *** = p ≤ 0.001.

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genes (Basel)