Image
|
Figure Caption
Fig. 4 Phosphorylated extracellularly regulated kinase (p-ERK) assay confirmation of gonadotropin-releasing hormone receptor (GnRHR) agonists. A, The Venn diagram shows the p-ERK assay confirmation rate of GnRHR agonist candidates in the HEK293-GnRHR cells. B to F, Concentration-response curves demonstrate that cholinergic agonists, including B, methacholine; C, bethanechol; D, (2-(acryloyloxy)ethyl)trimethylammonium; E, acetylcholine; and F, carbachol, stimulated ERK phosphorylation in HEK293-GnRHR cells but not in wild-type (WT) cells. All values represent the mean ± SD (n = 3 replicates).
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Endocrinology