FIGURE

Figure 5

ID

ZDB-FIG-250510-5

Publication

Aranda-Martínez et al., 2025 - Lack of asmt1 or asmt2 Yields Different Phenotypes and Malformations in Larvae to Adult Zebrafish

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Figure 5

Malformations in 5 dpf zebrafish larvae and 2-year-old adult zebrafish. (A) Some asmt1^+/− zebrafish showed edema, while in asmt1^−/−, all three types of malformation were found, and tail malformation was observed in asmt2^−/−, contrasting with WT and asmt2^+/−, which did not show any malformations. (B) Malformations were found to increase in the asmt1^+/− group, which were even greater in the homozygous lines. Scoliosis predominated in asmt1^−/− and caudal fin malformation in asmt2^−/−. However, asmt2^+/− did not exhibit any malformations. Data are presented as mean ± SEM (n = 5 larvae/group).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	asmt2^{sa11754/sa11754} (AB) asmt^gsz1/gsz1 (AB)
Observed In:	caudal fin vertebral column
Stage:	Adult

Phenotype Detail

Acknowledgments

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