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Fig. 2

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ZDB-FIG-250103-19

Publication

Kong et al., 2024 - Apigenin attenuates cisplatin-induced hair cell damage in the zebrafish lateral line

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Fig. 2

Apigenin protects against cisplatin-induced ROS accumulation and cell death in neuromasts. (A) TUNEL assay (red) and corresponding DAPI staining (blue) were performed in zebrafish in the presence/absence of apigenin (100 μM) and cisplatin (200 μM). (B) Quantification of TUNEL-positive cells per neuromast for each treatment, presented as mean ± SEM. (C) ROS generation detected by MitoSOX staining, followed by fluorescence microscopy imaging. (D) Quantification of MitoSOX fluorescent intensity for each treatment, presented as mean ± SEM. Statistical significance indicated as ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001. The scale bar equals 25 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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