FIGURE

Fig 6

ID

ZDB-FIG-241219-155

Publication

Chakraborty et al., 2024 - Functional investigation suggests CNTNAP5 involvement in glaucomatous neurodegeneration obtained from a GWAS in primary angle closure glaucoma

Other Figures

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Fig 6

Locomotory movement analysis of zebrafish.

A. Total distance moved (mm) of 96 hpf cntnap5 morpholino injected zebrafish (blue circles) and 96 hpf cntnap5 mismatch control (red circles) zebrafish for the light (left image) and light off (right image) periods. Left image, (light on) p = <0.0001, two-sided Mann–Whitney test, n = 24 cntnap5 morpholino injected zebrafish and n = 24 cntnap5 mismatch control, Right image (light off), p = 0.5767, bars = mean ± SEM ns not significant, ****p < 0.0001. B. Average distance moved (mm) of 96 hpf cntnap5 morpholino injected zebrafish (blue circles) and 5dpf cntnap5 mismatch control (red circles) zebrafish exposed to four cycles of 10 min light on and 10 min light off after 60-minutes habituation period. Each point represents 1 min, n = 24 cntnap5 mismatch control zebrafish and n = 24 cntnap5 morpholino injected zebrafish.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TU + MO1-cntnap5a + MO1-cntnap5b
Condition:	lighting conditions
Knockdown Reagents:	MO1-cntnap5a MO1-cntnap5b
Observed In:	swimming behavior
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.