FIGURE

Fig. S4

ID

ZDB-FIG-120810-42

Publication

Feng et al., 2012 - Live Imaging of Tumor Initiation in Zebrafish Larvae Reveals a Trophic Role for Leukocyte-Derived PGE(2)

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Fig. S4

Normal morphology of leukocyte-depleted morphants (related to Figure 3)

(A-G) Wide field images of morphants showing no general morphological defects; (H-N) Confocal images of anti-L-plastin immunostaining (magenta) of Lys:DsRed⁺ (green) larvae, showing no increase of L-plastin⁺ cells (magenta) or LysC:DsRed⁺ cells (green) in dmPGE₂ treated, pu1+gcsfr morphants (L), irf8 morphant (M) or gcsfr morphants (N), when compared with untreated equivalent morphants (I, J, K respectively). Scale bar=100μm.

Expression Data

Genes:	DsRed2 lcp1
Fish:	nz50Tg
Anatomical Terms:	macrophage neutrophil
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nz50Tg + MO1-irf8 nz50Tg + MO3-csf3r nz50Tg + MO1-spi1b + MO3-csf3r
Condition:	chemical treatment: prostaglandin E2
Knockdown Reagents:	MO1-irf8 MO1-spi1b MO3-csf3r
Observed In:	macrophage macrophage differentiation neutrophil neutrophil differentiation whole organism
Stage:	Day 4

Phenotype Detail

Acknowledgments

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