Fig. 8
- ID
- ZDB-FIG-091113-117
- Publication
- Sanek et al., 2009 - Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression
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Hh is necessary and sufficient for zic2a expression in the OS and ventral retina. (A-F) zic2a is expressed in the OS at 16s (A). In smo-/- mutants, zic2a expression is reduced in the OS at this stage (B, 14/14 embryos, n=2), but not elsewhere. shha mRNA-injected WT embryos express zic2a ectopically in the OS and retina at 16s (C, 13/13 embryos, n=1). zic2a expression is still reduced in smo-/- mutants at 19s (D,E, 30/30 embryos, n=2), and expanded in shha-injected retina (F, 19/19 embryos, n=1). The same result was observed at prim-5 (39/42 embryos, n=2, data not shown). Arrowheads point to the OS. Embryos are in lateral view, anterior to the left. |
Gene: | |
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Fish: | |
Anatomical Term: | |
Stage: | 14-19 somites |
Gene | Antibody | Fish | Conditions | Stage | Qualifier | Anatomy | Assay |
---|---|---|---|---|---|---|---|
zic2a | AB | standard conditions | 14-19 somites | ISH | |||
zic2a | smob641/b641 | standard conditions | 14-19 somites | ISH |