ZFIN Morpholino: MO1-csf3r

Target Location

Genome Build: GRCz11Chromosome: 16

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-csf3r

No data available

Phenotype

Phenotype resulting from MO1-csf3r

Phenotype	Fish	Figures
cell migration disrupted, abnormal	nz117Tg + MO1-csf3r	Fig. 4 from Liongue et al., 2009
granulocyte decreased amount, abnormal	WT + MO1-csf3r	Fig. 3 from Liongue et al., 2009
leukocyte aggregated, abnormal	WT + MO1-csf3r	Fig. 3 from Liongue et al., 2009
leukocyte decreased amount, abnormal	WT + MO1-csf3r	Fig. 3 from Liongue et al., 2009
myeloid cell aggregated, abnormal	WT + MO1-csf3r	Fig. 2 from Liongue et al., 2009

1 - 5 of 11 Show all

Phenotype of all Fish created by or utilizing MO1-csf3r

Phenotype	Fish	Conditions	Figures
myeloid cell decreased amount, abnormal	WT + MO1-csf3r	standard conditions	Fig. 2 from Liongue et al., 2009
myeloid cell aggregated, abnormal	WT + MO1-csf3r	standard conditions	Fig. 2 from Liongue et al., 2009
leukocyte aggregated, abnormal	WT + MO1-csf3r	standard conditions	Fig. 3 from Liongue et al., 2009
neutrophil decreased amount, abnormal	WT + MO1-csf3r	amputation: caudal fin	Fig. 4 from Hasegawa et al., 2017
rostral blood island mononuclear phagocyte aggregated, abnormal	WT + MO1-csf3r	standard conditions	Fig. 3 from Liongue et al., 2009

1 - 5 of 20 Show all

Citations

Include unpublished citations

Viana, F., Boucontet, L., Laghi, V., Schator, D., Ibranosyan, M., Jarraud, S., Colucci-Guyon, E., Buchrieser, C. (2023) Hiding in the yolk: A unique feature of Legionella pneumophila infection of zebrafish. PLoS pathogens. 19:e1011375e1011375
Meier, A.B., Basheer, F., Sertori, R., Laird, M., Liongue, C., Ward, A.C. (2022) Granulocyte Colony-Stimulating Factor Mediated Regulation of Early Myeloid Cells in Zebrafish. Frontiers in bioscience (Landmark edition). 27:110
Tsarouchas, T.M., Wehner, D., Cavone, L., Munir, T., Keatinge, M., Lambertus, M., Underhill, A., Barrett, T., Kassapis, E., Ogryzko, N., Feng, Y., van Ham, T.J., Becker, T., Becker, C.G. (2018) Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration. Nature communications. 9:4670
Hasegawa, T., Hall, C.J., Crosier, P.S., Abe, G., Kawakami, K., Kudo, A., Kawakami, A. (2017) Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold. eLIFE. 6
Halloum, I., Carrère-Kremer, S., Blaise, M., Viljoen, A., Bernut, A., Le Moigne, V., Vilchèze, C., Guérardel, Y., Lutfalla, G., Herrmann, J.L., Jacobs, W.R., Kremer, L. (2016) Deletion of a dehydratase important for intracellular growth and cording renders rough Mycobacterium abscessus avirulent. Proceedings of the National Academy of Sciences of the United States of America. 113(29):E4228-37
Lévesque, M., Feng, Y., Jones, R., and Martin, P. (2013) Inflammation drives wound hyperpigmentation by recruiting pigment cells to sites of tissue damage. Disease models & mechanisms. 6(2):508-515
Stachura, D.L., Svoboda, O., Campbell, C.A., Espín-Palazón, R., Lau, R.P., Zon, L.I., Bartunek, P., and Traver, D. (2013) The zebrafish granulocyte colony-stimulating factors (Gcsfs): 2 paralogous cytokines and their roles in hematopoietic development and maintenance. Blood. 122(24):3918-28
Liongue, C., Hall, C.J., O'Connell, B.A., Crosier, P., and Ward, A.C. (2009) Zebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration. Blood. 113(11):2535-2546

1 - 8 of 8

Show