ZFIN Morpholino: MO1-cebpb

Target Location

Genome Build: GRCz11Chromosome: 8

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-cebpb

No data available

Phenotype

Phenotype resulting from MO1-cebpb

Phenotype	Fish	Figures
head axin1 expression decreased amount, abnormal	WT + MO1-cebpb	Fig. 5 from Park et al., 2018

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Phenotype of all Fish created by or utilizing MO1-cebpb

Phenotype	Fish	Conditions	Figures
hindbrain macrophage acod1 expression amount, ameliorated	WT + MO1-cebpb	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 2 from Hall et al., 2013
macrophage acod1 expression amount, ameliorated	WT + MO1-cebpb	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 2 from Hall et al., 2013
midbrain macrophage acod1 expression amount, ameliorated	WT + MO1-cebpb	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 2 from Hall et al., 2013
head axin1 expression decreased amount, abnormal	WT + MO1-cebpb	control	Fig. 5 from Park et al., 2018
trunk acod1 expression amount, ameliorated	WT + MO1-cebpb	bacterial treatment by injection: Salmonella enterica subsp. enterica serovar Typhimurium	Fig. 2 from Hall et al., 2013

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Citations

Include unpublished citations

Doll, L., Welte, K., Skokowa, J., Bajoghli, B. (2024) A JAGN1-associated severe congenital neutropenia zebrafish model revealed an altered G-CSFR signaling and UPR activation. Blood advances. 8(15):4050-4065
Wu, J., Li, J., Chen, K., Liu, G., Zhou, Y., Chen, W., Zhu, X., Ni, T.T., Zhang, B., Jin, D., Li, D., Kang, L., Wu, Y., Zhu, P., Xie, P., Zhong, T.P. (2023) Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation. Proceedings of the National Academy of Sciences of the United States of America. 120:e2209062120e2209062120
Park, S., Lee, M.S., Gwak, J., Choi, T.I., Lee, Y., Ju, B.G., Kim, C.H., Oh, S. (2018) CCAAT/enhancer-binding protein-β functions as a negative regulator of Wnt/β-catenin signaling through activation of AXIN1 gene expression. Cell Death & Disease. 9:1023
Hall, C.J., Boyle, R.H., Astin, J.W., Flores, M.V., Oehlers, S.H., Sanderson, L.E., Ellett, F., Lieschke, G.J., Crosier, K.E., and Crosier, P.S. (2013) Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production. Cell Metabolism. 18(2):265-278
Hall, C.J., Flores, M.V., Oehlers, S.H., Sanderson, L.E., Lam, E.Y., Crosier, K.E., and Crosier, P.S. (2012) Infection-Responsive Expansion of the Hematopoietic Stem and Progenitor Cell Compartment in Zebrafish Is Dependent upon Inducible Nitric Oxide. Cell Stem Cell. 10(2):198-209
Powell, C., Elsaeidi, F., and Goldman, D. (2012) Injury-Dependent Muller Glia and Ganglion Cell Reprogramming during Tissue Regeneration Requires Apobec2a and Apobec2b. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(3):1096-1109
Rai, K., Sarkar, S., Broadbent, T.J., Voas, M., Grossmann, K.F., Nadauld, L.D., Dehghanizadeh, S., Hagos, F.T., Li, Y., Toth, R.K., Chidester, S., Bahr, T.M., Johnson, W.E., Sklow, B., Burt, R., Cairns, B.R., and Jones, D.A. (2010) DNA demethylase activity maintains intestinal cells in an undifferentiated state following loss of APC. Cell. 142(6):930-942
Eisinger, A.L., Nadauld, L.D., Shelton, D.N., Peterson, P.W., Phelps, R.A., Chidester, S., Stafforini, D.M., Prescott, S.M., and Jones, D.A. (2006) The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic Acid. The Journal of biological chemistry. 281(29):20474-20482

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