Gene
cebpb
- ID
- ZDB-GENE-020111-3
- Name
- CCAAT enhancer binding protein beta
- Symbol
- cebpb Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of gene expression; response to bacterium; and response to yeast. Predicted to be located in nucleus. Is expressed in several structures, including EVL; adipose tissue; digestive system; macrophage; and periderm. Orthologous to human CEBPB (CCAAT enhancer binding protein beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 46 figures from 26 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb380 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Park et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Additional Resources | Length | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily | CCAAT/enhancer-binding protein C/EBP | CCAAT/enhancer-binding protein, chordates |
---|---|---|---|---|---|---|
UniProtKB:Q7ZU07 | InterPro | 280 |
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- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Liu, L., Hu, W., Kerman, F.D., Spaink, H.P. (2025) Toll-like receptor adaptor protein TIRAP has specialized roles in signaling, metabolic control and leukocyte migration upon wounding in zebrafish larvae. International journal of biological sciences. 21:823841823-841
- Tesoriere, A., Ghirardo, R., Terrin, F., Sernesi, F., Meneghetti, G., Dalla Valle, L., Dinarello, A., Argenton, F. (2025) Tail Fin Regeneration in Zebrafish: The Role of Non-canonical Crosstalk Between STAT3 and Vitamin D Pathway. International journal of biological sciences. 21:271284271-284
- Doll, L., Welte, K., Skokowa, J., Bajoghli, B. (2024) A JAGN1-associated severe congenital neutropenia zebrafish model revealed an altered G-CSFR signaling and UPR activation. Blood advances. 8(15):4050-4065
- Gimenez, G., Kalev-Zylinska, M.L., Morison, I., Bohlander, S.K., Horsfield, J.A., Antony, J. (2024) Cohesin rad21 mutation dysregulates erythropoiesis and granulopoiesis output within the whole kidney marrow of adult zebrafish. American journal of physiology. Cell physiology. 328(1):C9-C19
- Li, G., Sun, Y., Kwok, I., Yang, L., Wen, W., Huang, P., Wu, M., Li, J., Huang, Z., Liu, Z., He, S., Peng, W., Bei, J.X., Ginhoux, F., Ng, L.G., Zhang, Y. (2024) Cebp1 and Cebpβ transcriptional axis controls eosinophilopoiesis in zebrafish. Nature communications. 15:811811
- Darroch, H., Keerthisinghe, P., Sung, Y.J., Rolland, L., Prankerd-Gough, A., Crosier, P.S., Astin, J.W., Hall, C.J. (2023) Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced mitochondrial bactericidal activity. Science advances. 9:eadf9904
- Jin, Q., Hu, Y., Gao, Y., Zheng, J., Chen, J., Gao, C., Peng, J. (2023) Hhex and Prox1a synergistically dictate the hepatoblast to hepatocyte differentiation in zebrafish. Biochemical and Biophysical Research Communications. 686:149182149182
- Lin, J., Zhan, G., Liu, J., Maimaitiyiming, Y., Deng, Z., Li, B., Su, K., Chen, J., Sun, S., Zheng, W., Yu, X., He, F., Cheng, X., Wang, L., Shen, B., Yao, Z., Yang, X., Zhang, J., He, W., Wu, H., Naranmandura, H., Chang, K.J., Min, J., Ma, J., Björklund, M., Xu, P.F., Wang, F., Hsu, C.H. (2023) YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths. National science review. 10:nwad227nwad227
- Wu, J., Li, J., Chen, K., Liu, G., Zhou, Y., Chen, W., Zhu, X., Ni, T.T., Zhang, B., Jin, D., Li, D., Kang, L., Wu, Y., Zhu, P., Xie, P., Zhong, T.P. (2023) Atf7ip and Setdb1 interaction orchestrates the hematopoietic stem and progenitor cell state with diverse lineage differentiation. Proceedings of the National Academy of Sciences of the United States of America. 120:e2209062120e2209062120
- Hason, M., Mikulasova, T., Machonova, O., Pombinho, A.R., van Ham, T.J., Irion, U., Nüsslein-Volhard, C., Bartunek, P., Svoboda, O. (2022) M-CSFR/CSF1R signaling regulates myeloid fates in zebrafish via distinct action of its receptors and ligands. Blood advances. 6(5):1474-1488
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