ZFIN Morpholino: MO1-fn1a

Target Location

Genome Build: GRCz11Chromosome: 9

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-fn1a

No data available

Phenotype

Phenotype resulting from MO1-fn1a

Phenotype	Fish	Figures
endoderm increased width, abnormal	ha01Tg + MO1-fn1a + MO4-tp53	Fig. S6 from Hu et al., 2018

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Phenotype of all Fish created by or utilizing MO1-fn1a

Phenotype	Fish	Conditions	Figures
endoderm increased width, abnormal	ha01Tg + MO1-fn1a + MO4-tp53	standard conditions	Fig. S6 from Hu et al., 2018
lateral rectus tissue regeneration delayed, abnormal	zf13Tg + MO1-fn1a	ablation: lateral rectus	Fig. 6 from Louie et al., 2017
lateral rectus tissue regeneration decreased efficacy, abnormal	zf13Tg + MO1-fn1a	ablation: lateral rectus	Fig. 6 from Louie et al., 2017
pharyngeal arch 1 decreased length, abnormal	s1pr1^ko311/ko311 + MO1-fn1a	standard conditions	Fig. 3 from Hisano et al., 2013
pharyngeal arch 1 decreased length, abnormal	s1pr2^ko322/ko322 + MO1-fn1a	standard conditions	Fig. 3 from Hisano et al., 2013

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Citations

Include unpublished citations

Hipke, K., Pitter, B., Hruscha, A., van Bebber, F., Modic, M., Bansal, V., Lewandowski, S.A., Orozco, D., Edbauer, D., Bonn, S., Haass, C., Pohl, U., Montanez, E., Schmid, B. (2023) Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1. Frontiers in cell and developmental biology. 11:11699621169962
Gao, Y., Hu, B., Flores, R., Xie, H., Lin, F. (2022) Fibronectin and Integrin α5 play overlapping and independent roles in regulating the development of pharyngeal endoderm and cartilage. Developmental Biology. 489:122-133
Mahabaleshwar, H., Asharani, P.V., Loo, T.Y., Koh, S.Y., Pitman, M.R., Kwok, S., Ma, J., Hu, B., Lin, F., Li Lok, X., Pitson, S.M., Saunders, T.E., Carney, T.J. (2022) Slit-Robo signalling establishes a Sphingosine-1-phosphate gradient to polarise fin mesenchyme. EMBO reports. 23(8):e54464
Naganathan, S.R., Popović, M., Oates, A.C. (2022) Left-right symmetry of zebrafish embryos requires somite surface tension. Nature. 605(7910):516-521
Prince, D.J., Jessen, J.R. (2019) Dorsal convergence of gastrula cells requires a Vangl2 and adhesion protein-dependent change in protrusive activity. Development (Cambridge, England). 146(22):
Rho, S.S., Kobayashi, I., Oguri-Nakamura, E., Ando, K., Fujiwara, M., Kamimura, N., Hirata, H., Iida, A., Iwai, Y., Mochizuki, N., Fukuhara, S. (2019) Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Developmental Cell. 49(5):681-696.e6
Hu, B., Gao, Y., Davies, L., Woo, S., Topczewski, J., Jessen, J.R., Lin, F. (2018) Glypican 4 and Mmp14 interact in regulating the migration of anterior endodermal cells by limiting extracellular matrix deposition. Development (Cambridge, England). 145(17):
Love, A.M., Prince, D.J., Jessen, J.R. (2018) Vangl2-dependent regulation of membrane protrusions and directed migration requires a fibronectin extracellular matrix. Development (Cambridge, England). 145(22):
Louie, K.W., Saera-Vila, A., Kish, P.E., Colacino, J.A., Kahana, A. (2017) Temporally distinct transcriptional regulation of myocyte dedifferentiation and Myofiber growth during muscle regeneration. BMC Genomics. 18:854
Araya, C., Carmona-Fontaine, C., Clarke, J.D. (2016) ECM couples the convergence movements of mesoderm and neural plate during the early stages of neurulation. Developmental Dynamics : an official publication of the American Association of Anatomists. 245(5):580-9

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