ZFIN Morpholino: MO1-fgf3

Target Location

Genome Build: GRCz11Chromosome: 7

Genomic Features

No data available

Expression

Gene expression in Wild Types + MO1-fgf3

No data available

Phenotype

Phenotype resulting from MO1-fgf3

Phenotype	Fish	Figures
adenohypophysis morphogenesis process quality, abnormal	zf44Tg + MO1-fgf3	Fig. 2 , Fig. 3 , Fig. 4 , Fig. 5 from Liu et al., 2008
basibranchial aplastic, abnormal	WT + MO1-fgf3	Fig. 4 from Hanaoka et al., 2004
ceratobranchial cartilage absent, abnormal	AB + MO1-fgf3	Fig. 3 from Lin et al., 2013
ceratohyal cartilage aplastic, abnormal	WT + MO1-fgf3	Fig. 4 from Hanaoka et al., 2004
ceratohyal cartilage malformed, abnormal	AB + MO1-fgf3	Fig. 3 from Lin et al., 2013

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Phenotype of all Fish created by or utilizing MO1-fgf3

Phenotype	Fish	Conditions	Figures
pharyngeal arch 4 has fewer parts of type cranial neural crest, abnormal	AB + MO1-fgf3	standard conditions	Fig. 3 from Lin et al., 2013
pharyngeal arch 3-7 skeleton absent, abnormal	AB + MO1-fgf3	standard conditions	Fig. 3 from Lin et al., 2013
ceratobranchial cartilage absent, abnormal	AB + MO1-fgf3	standard conditions	Fig. 3 from Lin et al., 2013
ceratohyal cartilage malformed, abnormal	AB + MO1-fgf3	standard conditions	Fig. 3 from Lin et al., 2013
epibranchial field sox3 expression decreased amount, abnormal	WT + MO1-fgf3	standard conditions	Fig. 5 from Sun et al., 2007

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Citations

Include unpublished citations

Leino, S.A., Constable, S.C.J., Streit, A., Wilkinson, D.G. (2023) Zbtb16 mediates a switch between Fgf signalling regimes in the developing hindbrain. Development (Cambridge, England). 150(18):
Osborn, D.P.S., Li, K., Cutty, S.J., Nelson, A.C., Wardle, F.C., Hinits, Y., Hughes, S.M. (2020) Fgf-driven Tbx protein activities directly induce myf5 and myod to initiate zebrafish myogenesis. Development (Cambridge, England). 147(8):
Goldshmit, Y., Tang, J.K.K.Y., Siegel, A.L., Nguyen, P.D., Kaslin, J., Currie, P.D., Jusuf, P.R. (2018) Different Fgfs have distinct roles in regulating neurogenesis after spinal cord injury in zebrafish. Neural Development. 13:24
van Boxtel, A.L., Chesebro, J.E., Heliot, C., Ramel, M.C., Stone, R.K., Hill, C.S. (2015) A Temporal Window for Signal Activation Dictates the Dimensions of a Nodal Signaling Domain. Developmental Cell. 35:175-185
Miyake, A., Chitose, T., Kamei, E., Murakami, A., Nakayama, Y., Konishi, M., Itoh, N. (2014) Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain. PLoS One. 9:e110836
Kuo, C.L., Lam, C.M., Hewitt, J.E., and Scotting, P.J. (2013) Formation of the Embryonic Organizer Is Restricted by the Competitive Influences of Fgf Signaling and the SoxB1 Transcription Factors. PLoS One. 8(2):e57698
Lin, C.Y., Lee, H.C., Chen, H.C., Hsieh, C.C., and Tsai, H.J. (2013) Normal Function of Myf5 During Gastrulation Is Required for Pharyngeal Arch Cartilage Development in Zebrafish Embryos. Zebrafish. 10(4):486-99
McCarroll, M.N., and Nechiporuk, A.V. (2013) Fgf3 and Fgf10a work in concert to promote maturation of the epibranchial placodes in zebrafish. PLoS One. 8(12):e85087
Miyake, A., and Itoh, N. (2013) Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development. Biology Open. 2(5):515-524
Simões, F.C., Peterkin, T., and Patient, R. (2011) Fgf differentially controls cross-antagonism between cardiac and haemangioblast regulators. Development (Cambridge, England). 138(15):3235-3245

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