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FIGURE 5
Coilin N‐terminal mutation impairs the activation of immunity‐related pathways. (A) Heatmap of the top 30 differentially expressed genes for WT and coilin mutant (ΔN1 and ΔN2) embryos injected with PBS (blue horizontal bar) or LPS (green horizontal bar). (B, D, F) GO enrichment analysis illustrating the top general pathways altered under PBS versus LPS comparisons in WT and mutants. (C, E, G) REVIGO analysis illustrating the top immunity‐related pathways altered under PBS versus LPS comparisons in WT and mutants.
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Full text @ FASEB J.