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Fig. 6 Inflammation and Jak1-Stat3 signaling regulate MG status transition during zebrafish retina regeneration.(A) qPCR analysis comparing the expression of MG subtype markers in uninjured control (0 d) and PBS- or Dex-treated zebrafish retinas 12 hours or 1 day post-injury. (B) qPCR analysis of the expression of MG subtype markers in uninjured control (0 d) and DMSO- or JSI-124–treated zebrafish retinas 12 hours or 1 day post-injury. (C) qPCR demonstrating the expression of MG subtype markers in uninjured control (0 d) and Zym-treated retinas 1 day post-injection. *P < 0.05, **P < 0.01, ***P < 0.001, vs. PBS or DMSO control in A and B, and with uninjured control in C (Student’s t-test [two tails, unpaired]). Dex: Dexamethasone; DMSO: dimethyl sulfoxide; MG: Müller glia; PBS: phosphate-buffered saline; qPCR: quantitative polymerase chain reaction; Zym: zymosan A.