|
Fig. 4 Analysis of cell-cell interactions between immune cells and MG in intact and stab-injured zebrafish retinas.(A) CellphoneDB analysis showing possible cell-cell interactions within the retina. (B, C) The number of interactions between MG and microglia and other cell types, as assessed using CellphoneDB. (D) The number of interactions among different MG and microglia subtypes together with rod progenitor cells. (E, F) The number of interactions among microglia-1 and microglia-2 and other microglia and MG subtypes. (G, H) List of the most significant ligand-receptor pairs identified between microglia and MG. microglia to MG, ligand expressed by microglia and receptor expressed by MG; MG to microglia, vice versa; awg expression, the average expression level of target pairs in both cells; rank, the distinctiveness of identified pairs in MG and microglia compared to other cell types; MG: Müller glia.