ZFIN Image: Kondrychyn et al., 2025, Fig. 5

Image

Figure Caption

Fig. 5 Aquaporin-mediated water influx increases tip cell volume. (A–C) Representative maximum intensity projection confocal z-stacks of tip cell and its 3D-volume rendering of 25 hpf wildtype (A), aqp1a.1rk28/rk28;aqp8a.1rk29/rk29 (B) and wildtype embryos overexpressing Aqp1a.1 (C) labeled with cytosolic mEmerald or EGFP. Scale bar, 10 µm. (D) Quantification of tip cell volume in 25 hpf wildtype (n = 24 cells) and aqp1a.1rk28/rk28;aqp8a.1rk29/rk29 (n = 20 cells) and wildtype overexpressing Aqp1a.1 (n = 32 cells) embryos from three independent experiments. Statistical significance was determined by Brown–Forsythe and Welch ANOVA tests. *p<0.05, **p<0.01, and ****p<0.0001.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Elife