ZFIN Image: Hu et al., 2025, Fig. 8

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Figure Caption

Fig. 8

Axon regeneration into the optic tectum is dependent upon the mevalonate synthesis pathway. (A) Axon regeneration into the optic tectum is reduced upon hmgcra + hmgcrb knockdown (hmgcra + b-MO), rescued by daily supplementation with mevalonate (MVA), and accelerated by MVA treatment alone. (B) Quantification of axon regeneration in each treatment group. Colored boxes represent p < 0.05 in treated groups compared with the C-MO and/or Vehicle treated group in the corresponding column by two-way ANOVA with Fisher’s LSD post hoc test, n = 5–6 for each group. Scale bar = 500 μm

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Mol. Neurodegener.