ZFIN Image: Men et al., 2024, Figure 1

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Figure 1

PER3 expression is significantly downregulated in several cancers, including GBM. (A) TCGA database analysis showed the expression levels of PER3 in 33 cancer tissues and their corresponding surrounding normal tissues. * p < 0.05; ** p < 0.01; *** p < 0.001. (B–D) The expression levels of PER3 in cases (B) GSE29458, (C) GSE22866, and (D) GSE14805 in GBM tissues had significantly higher expression levels than normal brain tissues. (E,F) The 706 GBM patients in the TCGA-GBMLGG database were categorized into high-expression and low-expression groups based on the median PER3 expression level. (E) Volcano plot and (F) heat map demonstrating the expression levels of specific mRNAs in GBM patients.

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