ZFIN Image: Liu et al., 2025, Figure 4

Image

Figure Caption

Figure 4

Schematic diagram of significantly differentially expressed genes (DEGs) in the representative pathways in myd88 mutant zebrafish larvae compared to the wild type controls. (A) Glycolysis and gluconeogenesis, TCA cycle and oxidative phosphorylation related pathways. (B) TLR-associated signaling pathways. (C) Calcium regulation-related pathways. (D) Ribosome-associated pathway. The significance was established as padj value less than 0.05. Red arrows represent significantly upregulated DEGs, blue arrows represent significantly downregulated DEGs. The link between TIRAP and PIK3AP1 refers to Luo, et al.59. The link between CREB and DHPR refers to Antony, et al.44. Other links refer to KEGG Pathway Database (https://www.genome.jp/kegg/pathway.html).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Biol. Sci.