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Fig. 3 TTZ inhibits HUVEC angiogenic activities in a dose-dependent manner. (A) TTZ inhibits HUVEC proliferation in the BrdU assay. (B-D) TTZ treatment leads to reduced tube extension and branching during tubulogenesis. (E-F) Wound healing assay showing anti-migratory effect of TTZ. Concentrations are log-scaled , and biological replicates are represented using different colors. Asterisks denote statistical significance: *p < 0.01; **p < 0.001.
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