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Iwasaki et al., 2019 - Essential role of prostaglandin E₂ and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis

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Figure 5

COX1-derived PGE₂ is involved in the lymphatic specification. (A) Expression of COX1, COX2a, and COX2b was analyzed by WISH at 24 hpf. (B) Zebrafish embryos were treated with Veh or SC-560 (25 μM) in the absence or presence of Sulp (10 μM) from 0 to 24 hpf, and the expression of lyve1b was analyzed by WISH at 24 hpf. The number at the bottom right of each panel indicates the number of embryos demonstrating the phenotype shown in the panel over the total number of embryos analyzed in a representative experiment.

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