Gene

hoxc6a

ID
ZDB-GENE-990415-113
Name
homeobox C6a
Symbol
hoxc6a Nomenclature History
Previous Names
  • hoxc-6
  • hoxc6
  • etID228114.23 (1)
  • ZF-61
  • zgc:101882
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including ectoderm; mesoderm; nervous system; pectoral fin; and somite. Orthologous to human HOXC6 (homeobox C6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
31 figures from 15 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Maeno et al., 2024
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa12505Allele with one point mutationUnknownSplice SiteENU
sud122Allele with one deletionExon 1UnknownCRISPR
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-hoxc6a (2)
MO1-hoxc6aN/ASundaramoorthi et al., 2023
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Human Disease
Associated With hoxc6a Human Ortholog
No data available
Associated With hoxc6a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR001827 Homeobox protein, antennapedia type, conserved site
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR020479 Homeodomain, metazoa
Family IPR050296 Antennapedia-type homeobox
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Domain Details Per Protein
Protein Additional Resources Length Antennapedia-type homeobox Homedomain-like superfamily Homeobox, conserved site Homeobox protein, antennapedia type, conserved site Homeodomain Homeodomain, metazoa
UniProtKB:P15862 InterPro 231
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 23
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hoxc6a-201 (1) Ensembl 757 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-81P22ZFIN Curated Data
EncodesESTeu620Thisse et al., 2005
EncodesESTIMAGE:7140528Thisse et al., 2004
EncodescDNAMGC:101882ZFIN Curated Data
EncodescDNAMGC:192224ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanHOXC612
Amino acid sequence comparison (1)
Nucleotide sequence comparison (1)
Conserved genome location (synteny) (2)
MouseHoxc615
Nucleotide sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
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