Gene

foxa3

ID
ZDB-GENE-980526-423
Name
forkhead box A3
Symbol
foxa3 Nomenclature History
Previous Names
  • fa11c04
  • fc37a08
  • fkd2 (1)
  • forkhead-2
  • wu:fa11c04
  • wu:fc37a08
  • zf-FKH1
  • Zffkh1
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including hatching gland development; nervous system development; and neural plate anterior/posterior regionalization. Located in nucleus. Is expressed in several structures, including axial mesoderm; digestive system; endoderm; germ ring; and hatching gland. Orthologous to human FOXA3 (forkhead box A3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
180 figures from 150 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
ihb162Allele with one deletionUnknownUnknownCRISPR
ihb163Allele with one deletionUnknownUnknownCRISPR
la013319TgTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
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Human Disease
Associated With foxa3 Human Ortholog
No data available
Associated With foxa3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018122 Fork head domain conserved site1
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Domain IPR013638 Fork-head N-terminal
Domain IPR018533 Forkhead box protein, C-terminal
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Domain Details Per Protein
Protein Additional Resources Length Forkhead box domain-containing protein Forkhead box protein, C-terminal Fork head domain Fork head domain conserved site1 Fork head domain conserved site 2 Fork-head N-terminal Hepatocyte nuclear factor 3-gamma, forkhead domain Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:O73778 InterPro 441
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 18
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA foxa3-201 (1) Ensembl 2,763 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-foxa3 polyclonal Rabbit
  • IHC
2
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-223N17ZFIN Curated Data
EncodesESTfa11c04
EncodesESTfc37a08
EncodescDNAMGC:194053ZFIN Curated Data
EncodescDNAMGC:194065ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanFOXA319
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
MouseFoxa37
Conserved genome location (synteny) (1)
Amino acid sequence comparison (2)
Phylogenetic tree (1)
Citations
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