Gene

golga2

ID

ZDB-GENE-081030-1

Name

golgin A2

Symbol

golga2 Nomenclature History

Previous Names

cis-Golgi matrix protein GM130
drgm130
si:dkey-246l19.1

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Acts upstream of or within brain development; skeletal muscle tissue development; and thigmotaxis. Predicted to be located in Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment membrane; and microtubule cytoskeleton. Predicted to be active in Golgi cis cisterna; Golgi cisterna membrane; and cis-Golgi network. Is expressed in otic vesicle. Orthologous to several human genes including GOLGA2 (golgin A2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Shamseldin et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With golga2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Developmental delay with hypotonia, myopathy, and brain abnormalities	620240

Associated With golga2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR043937	Golgin subfamily A member 2, C-terminal binding motif
Domain	IPR043976	Golgin subfamily A, conserved domain
Family	IPR024858	Golgin subfamily A

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M3B239	InterPro	1056
UniProtKB:A0A8M3ARU7	InterPro	1027
UniProtKB:A0A8M2BFH4	InterPro	1024
UniProtKB:A0A8M3AS19	InterPro	1059
UniProtKB:A1IH00	InterPro	1028
UniProtKB:A0A8M2BFH8	InterPro	996
UniProtKB:A0A8M3AZ71	InterPro	1031
UniProtKB:A0A8M3B9A6	InterPro	999

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	golga2-201 (1) Ensembl	Ensembl	3,517 nt	Select Tool ZFIN BLAST
mRNA	golga2-203 (1) Ensembl	Ensembl	250 nt	Select Tool ZFIN BLAST
mRNA	golga2-204 (1) Ensembl	Ensembl	540 nt	Select Tool ZFIN BLAST
mRNA	golga2-205 (1) Ensembl	Ensembl	513 nt	Select Tool ZFIN BLAST
ncRNA	golga2-002 (1) Ensembl	Ensembl	612 nt	Select Tool ZFIN BLAST
ncRNA	golga2-003 (1) Ensembl	Ensembl	456 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-golga2	monoclonal	golga2	IgG1 , k	Mouse	IHC	BD Biosciences	17

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations