Gene

golga2

ID
ZDB-GENE-081030-1
Name
golgin A2
Symbol
golga2 Nomenclature History
Previous Names
  • cis-Golgi matrix protein GM130
  • drgm130
  • si:dkey-246l19.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Acts upstream of or within brain development; skeletal muscle tissue development; and thigmotaxis. Predicted to be located in Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment membrane; and microtubule cytoskeleton. Predicted to be active in Golgi cis cisterna; Golgi cisterna membrane; and cis-Golgi network. Is expressed in otic vesicle. Orthologous to several human genes including GOLGA2 (golgin A2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Shamseldin et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa20328Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
MO1-golga2N/AShamseldin et al., 2016
MO2-golga2N/AShamseldin et al., 2016
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Human Disease
Associated With golga2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Developmental delay with hypotonia, myopathy, and brain abnormalities 620240
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Associated With golga2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR043937 Golgin subfamily A member 2, C-terminal binding motif
Domain IPR043976 Golgin subfamily A, conserved domain
Family IPR024858 Golgin subfamily A
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Domain Details Per Protein
Protein Additional Resources Length Golgin subfamily A Golgin subfamily A, conserved domain Golgin subfamily A member 2, C-terminal binding motif
UniProtKB:A0A8M3B239 InterPro 1056
UniProtKB:A0A8M3ARU7 InterPro 1027
UniProtKB:A0A8M2BFH4 InterPro 1024
UniProtKB:A0A8M3AS19 InterPro 1059
UniProtKB:A1IH00 InterPro 1028
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA golga2-201 (1) Ensembl 3,517 nt
mRNA golga2-203 (1) Ensembl 250 nt
mRNA golga2-204 (1) Ensembl 540 nt
mRNA golga2-205 (1) Ensembl 513 nt
ncRNA golga2-002 (1) Ensembl 612 nt
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Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-golga2 monoclonal IgG1 , k Mouse
  • IHC
BD Biosciences
17
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Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-89I7ZFIN Curated Data
Contained inBACDKEY-246L19ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanGOLGA29
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Functional complementation (1)
MouseGolga22
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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