Gene

panx1b

ID
ZDB-GENE-070705-192
Name
pannexin 1b
Symbol
panx1b Nomenclature History
Previous Names
  • si:ch211-69i14.7
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Enables voltage-gated channel activity and wide pore channel activity. Acts upstream of or within detection of light stimulus involved in visual perception and swimming behavior. Located in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Is expressed in several structures, including central nervous system; eye; heart; liver; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human PANX1 (pannexin 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa40513Allele with one point mutationUnknownPremature StopENU
yku2Allele with one deletionExon 4UnknownTALEN
nhi7Allele with one deletionUnknownUnknownTALEN
1 - 3 of 3
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
TALEN1-panx1b (4)
1 - 1 of 1
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Human Disease
Associated With panx1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Oocyte/zygote/embryo maturation arrest 7 618550
1 - 1 of 1
Associated With panx1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR000990 Innexin
Family IPR039099 Pannexin
1 - 2 of 2
Domain Details Per Protein
Protein Additional Resources Length Innexin Pannexin
UniProtKB:A0A8M9Q3P2 InterPro 259
UniProtKB:F1QSR7 InterPro 422
1 - 2 of 2
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA panx1b-201 (1) Ensembl 2,881 nt
1 - 1 of 1
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-panx1b polyclonal IgG Rabbit
  • IHC
1
Ab1-panx1b IgY Chicken
  • IHC
1
1 - 2 of 2
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-69I14ZFIN Curated Data
Contained inBACCH211-139A5ZFIN Curated Data
1 - 2 of 2
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanPANX111
Amino acid sequence comparison (1)
MousePanx19
Amino acid sequence comparison (2)
Conserved genome location (synteny) (1)
Citations
1 - 9 of 9
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