Gene
ccnb3
- ID
- ZDB-GENE-060929-684
- Name
- cyclin B3
- Symbol
- ccnb3 Nomenclature History
- Previous Names
-
- zgc:153369
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle. Predicted to act upstream of or within cell division and mitotic cell cycle phase transition. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in female organism; spermatocyte; spermatogonium; and testis. Orthologous to human CCNB3 (cyclin B3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Cyclin | Cyclin A/B-like | Cyclin, C-terminal domain | Cyclin-like domain | Cyclin-like superfamily | Cyclin, N-terminal |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q08C91 | InterPro | 398 |
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Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | CH211-117O2 | ZFIN Curated Data | |
| Contained in | BAC | DKEY-171C9 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:153369 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:174595 | ZFIN Curated Data |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001076719 (1) | 1735 nt | ||
| Genomic | GenBank:CR381635 (2) | 173058 nt | ||
| Polypeptide | UniProtKB:Q08C91 (1) | 398 aa |
- Guo, D., Xiong, H., Yang, Z., Zhang, R., Shi, P., Yao, Y., Liu, M., Xu, C., Wang, Q.K. (2024) Lysosomal membrane protein TMEM106B modulates hematopoietic stem and progenitor cell proliferation and differentiation by regulating LAMP2A stability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 38:e23870e23870
- Zhang, Y., Li, R., Li, H., Huang, Y., Mei, Y., Zheng, Y., Guo, Y., Zhou, Z., Yong, Z., Zhao, Y., Dong, W., Gao, J., Cao, X. (2024) Morpho-histological and Transcriptome Analysis Reveal the Unreduced Sperm Formation Mechanism in cdk1-Depletion Zebrafish. Marine biotechnology (New York, N.Y.). 26(6):1206-1218
- Koslow, M., Zhu, P., McCabe, C., Xu, X., Lin, X. (2023) Kidney transcriptome and cystic kidney disease genes in zebrafish. Frontiers in Physiology. 14:11840251184025
- Zuppo, D.A., Missinato, M.A., Santana-Santos, L., Li, G., Benos, P.V., Tsang, M. (2023) Foxm1 regulates cardiomyocyte proliferation in adult zebrafish after cardiac injury. Development (Cambridge, England). 150(6):
- Cao, L., Fang, H., Yan, D., Wu, X.M., Zhang, J., Chang, M.X. (2022) CD44a functions as a regulator of p53 signaling, apoptosis and autophagy in the antibacterial immune response. Communications biology. 5:889
- Karasu, M.E., Bouftas, N., Keeney, S., Wassmann, K. (2019) Cyclin B3 promotes anaphase I onset in oocyte meiosis. The Journal of cell biology. 218(4):1265-1281
- Bednarek, D., González-Rosa, J.M., Guzmán-Martínez, G., Gutiérrez-Gutiérrez, Ó., Aguado, T., Sánchez-Ferrer, C., Marques, I.J., Galardi-Castilla, M., de Diego, I., Gómez, M.J., Cortés, A., Zapata, A., Jiménez-Borreguero, L.J., Mercader, N., Flores, I. (2015) Telomerase Is Essential for Zebrafish Heart Regeneration. Cell Reports. 12(10):1691-703
- Biswas, G., Kinoshita, S., Kono, T., Hikima, J.I., Sakai, M. (2015) Evolutionary evidence of tumor necrosis factor super family members in the Japanese pufferfish (Takifugu rubripes): Comprehensive genomic identification and expression analysis. Marine genomics. 22:25-36
- Yue, H., Li, C., Du, H., Zhang, S., Wei, Q. (2015) Sequencing and De Novo Assembly of the Gonadal Transcriptome of the Endangered Chinese Sturgeon (Acipenser sinensis). PLoS One. 10:e0127332
- Ozaki, Y., Saito, K., Shinya, M., Kawasaki, T., and Sakai, N. (2011) Evaluation of Sycp3, Plzf and Cyclin B3 expression and suitability as spermatogonia and spermatocyte markers in zebrafish. Gene expression patterns : GEP. 11(5-6):309-315
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