Gene

plvapb

ID
ZDB-GENE-060616-96
Name
plasmalemma vesicle associated protein b
Symbol
plvapb Nomenclature History
Previous Names
  • plvap
  • Dr.9655 (1)
  • fb11a07
  • vsg1 (1)
  • wu:fb11a07
  • zgc:113451
  • zgc:136228 (1)
  • zvsg1 (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Acts upstream of or within Notch signaling pathway and regulation of vascular permeability. Predicted to be located in membrane. Is expressed in vasculature. Human ortholog(s) of this gene implicated in congenital diarrhea. Orthologous to human PLVAP (plasmalemma vesicle associated protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
11 figures from 9 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from Gordon et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa13080Allele with one point mutationUnknownPremature StopENU
sa18400Allele with one point mutationUnknownPremature StopENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With plvapb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Diarrhea 10, protein-losing enteropathy type 618183
1 - 1 of 1
Associated With plvapb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR009538 Plasmalemma vesicle-associated protein
1 - 1 of 1
Domain Details Per Protein
Protein Additional Resources Length Plasmalemma vesicle-associated protein
UniProtKB:F1Q8W5 InterPro 409
UniProtKB:Q1ED33 InterPro 409
UniProtKB:Q58EJ6 InterPro 409
1 - 3 of 3
Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA plvapb-201 (1) Ensembl 2,019 nt
ncRNA vsg1-002 (1) Ensembl 725 nt
1 - 2 of 2
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(plvapb:EGFP)
  • plvapb
  • Danio rerio
1 (5)
1 - 1 of 1
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEY-67M7ZFIN Curated Data
EncodesESTfb11a07
EncodescDNAMGC:113451ZFIN Curated Data
EncodescDNAMGC:136228ZFIN Curated Data
EncodescDNAMGC:192924ZFIN Curated Data
1 - 5 of 5
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanPLVAP19
Phylogenetic tree (1)
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
MousePlvap8
Conserved genome location (synteny) (1)
Phylogenetic tree (1)
Amino acid sequence comparison (1)
Citations
1 - 10 of 19
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