Gene

krt17

ID
ZDB-GENE-060503-86
Name
keratin 17
Symbol
krt17 Nomenclature History
Previous Names
  • si:dkeyp-113d7.7
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to be a structural constituent of skin epidermis. Acts upstream of or within fin regeneration. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Is expressed in EVL; eye; and trunk. Human ortholog(s) of this gene implicated in several diseases, including ectodermal dysplasia (multiple); focal nonepidermolytic palmoplantar keratoderma 1; pachyonychia congenita; steatocystoma multiplex; and white sponge nevus 2. Orthologous to several human genes including KRT13 (keratin 13); KRT14 (keratin 14); and KRT15 (keratin 15).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa23427Allele with one point mutationUnknownMissense, Splice SiteENU
sa29144Allele with one point mutationUnknownPremature StopENU
sa43209Allele with one point mutationUnknownSplice SiteENU
sa43210Allele with one point mutationUnknownPremature StopENU
1 - 4 of 4
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Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-krt17
    (2)
    CRISPR2-krt17
      (2)
      1 - 2 of 2
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      Human Disease
      Associated With krt17 Human Ortholog
      No data available
      Associated With krt17 Via Experimental Models
      No data available
      Gene Ontology
      Protein Domains
      Domain, Family, and Site Summary
      Type InterPro ID Name
      Domain IPR039008 Intermediate filament, rod domain
      Family IPR002957 Keratin, type I
      1 - 2 of 2
      Domain Details Per Protein
      Protein Additional Resources Length Intermediate filament, rod domain Keratin, type I
      UniProtKB:Q1LXJ1 InterPro 423
      1 - 1 of 1
      Transcripts
      Genome Browsers
      Genome Build: GRCz11Chromosome: 19
      Type Name Annotation Method Has Havana Data Length (nt) Analysis
      mRNA krt17-201 (1) Ensembl 1,500 nt
      mRNA krt17-202 (1) Ensembl 869 nt
      1 - 2 of 2
      Interactions and Pathways
      No data available
      Antibodies
      Name Type Antigen Genes Isotype Host Organism Assay Source Citations
      Ab1-krt17 monoclonal IgG2b Mouse
      • WB
      Thermo Scientific Pierce Protein Research Products
      3
      1 - 1 of 1
      Plasmids
      No data available
      Constructs
      No data available
      Marker Relationships
      Relationship Marker Type Marker Accession Numbers Citations
      Contained inBACDKEYP-113D7ZFIN Curated Data
      EncodescDNAMGC:174182ZFIN Curated Data
      1 - 2 of 2
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      Sequences
      Orthology
      Comparative Orthology
      Alliance
      Gene Tree
      Ensembl
      No data available
      Citations
      1 - 10 of 18
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