Gene

cavin4b

ID
ZDB-GENE-041212-87
Name
caveolae associated protein 4b
Symbol
cavin4b Nomenclature History
Previous Names
  • murc (1)
  • murcb
  • wu:fc18g06
  • zgc:92239 (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Acts upstream of or within T-tubule organization and skeletal muscle fiber development. Predicted to be located in membrane. Predicted to be active in caveola and cytoplasm. Is expressed in several structures, including adaxial cell; dorsal habenular nucleus; musculature system; pectoral fin bud; and somite. Used to study muscular dystrophy. Orthologous to human CAVIN4 (caveolae associated protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Housley et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
s983Allele with one delinsUnknownMissenseTALEN
uq6rpAllele with one point mutationExon 1UnknownENU
1 - 2 of 2
Show
Sequence Targeting Reagents
Targeting Reagent Created Alleles Citations
CRISPR1-cavin4b
    (2)
    TALEN1-cavin4bHousley et al., 2016
    1 - 2 of 2
    Show
    Human Disease
    Associated With cavin4b Human Ortholog
    No data available
    Associated With cavin4b Via Experimental Models
    1 - 1 of 1
    Gene Ontology
    Protein Domains
    Domain, Family, and Site Summary
    Type InterPro ID Name
    Family IPR026752 Cavin family
    1 - 1 of 1
    Domain Details Per Protein
    Protein Additional Resources Length Cavin family
    UniProtKB:Q5PQY9 InterPro 318
    1 - 1 of 1
    Transcripts
    Genome Browsers
    Genome Build: GRCz11Chromosome: 24
    Type Name Annotation Method Has Havana Data Length (nt) Analysis
    mRNA cavin4b-201 (1) Ensembl 3,492 nt
    1 - 1 of 1
    Interactions and Pathways
    No data available
    Antibodies
    Name Type Antigen Genes Isotype Host Organism Assay Source Citations
    Ab1-murc polyclonal Rabbit
    • IHC
    Sigma-Aldrich
    2
    1 - 1 of 1
    Plasmids
    Constructs
    Construct Regulatory Region Coding Sequence Species Tg Lines Citations
    Tg(actc1b:cavin4b-mClover)
    • Danio rerio
    1 (2)
    1 - 1 of 1
    Show
    Marker Relationships
    Relationship Marker Type Marker Accession Numbers Citations
    Contained inBACDKEYP-87A6ZFIN Curated Data
    EncodesESTfc18g06
    EncodescDNAMGC:92239ZFIN Curated Data
    1 - 3 of 3
    Show
    Sequences
    Orthology
    Comparative Orthology
    Alliance
    Gene Tree
    Ensembl
    Species Symbol Chromosome Accession # Evidence
    HumanCAVIN49
    Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    MouseCavin44
    Conserved genome location (synteny) (1)
    Amino acid sequence comparison (1)
    Citations
    1 - 10 of 16
    Show