Gene

foxj1b

ID
ZDB-GENE-041212-76
Name
forkhead box J1b
Symbol
foxj1b Nomenclature History
Previous Names
  • foxj1.2 (1)
  • fj67h07
  • wu:fj67h07 (1)
  • zgc:101713 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within embryonic organ morphogenesis and motile cilium assembly. Predicted to be active in nucleus. Is expressed in several structures, including axis; germ ring; mesoderm; nervous system; and pronephros. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 43. Orthologous to human FOXJ1 (forkhead box J1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 18 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
la012142TgTransgenic insertionUnknownUnknownDNA
la018100TgTransgenic insertionUnknownUnknownDNA
sa9105Allele with one point mutationUnknownPremature StopENU
sa22082Allele with one point mutationUnknownPremature StopENU
sq5719Allele with one delinsUnknownUnknownCRISPR
tsu10GtTransgenic insertionUnknownUnknownDNA
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Sequence Targeting Reagents
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Human Disease
Associated With foxj1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 43 Alliance Ciliary dyskinesia, primary, 43 618699
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Associated With foxj1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018122 Fork head domain conserved site1
Conserved_site IPR030456 Fork head domain conserved site 2
Domain IPR001766 Fork head domain
Domain IPR047512 Forkhead box protein J1, forkhead domain
Family IPR047513 Forkhead box protein J1
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Domain Details Per Protein
Protein Additional Resources Length Forkhead box protein J1 Forkhead box protein J1, forkhead domain Fork head domain Fork head domain conserved site1 Fork head domain conserved site 2 Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:F1R8Z9 InterPro 442
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 12
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA foxj1b-201 (1) Ensembl 2,316 nt
mRNA foxj1b-202 (1) Ensembl 828 nt
mRNA foxj1b-203 (1) Ensembl 1,343 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Construct Regulatory Region Coding Sequence Species Tg Lines Citations
Tg(hsp70l:foxj1b-HA)
  • foxj1b
  • Danio rerio
1 (2)
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Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH73-197A13ZFIN Curated Data
EncodesESTfj67h07
EncodescDNAMGC:101713ZFIN Curated Data
EncodescDNAMGC:192900ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanFOXJ117
Amino acid sequence comparison (1)
MouseFoxj111
Amino acid sequence comparison (1)
Citations
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